The Argentine maestro provided two assists as goals from Luiz Suarez, Antoine Griezmann, and Ansu Fati eased Barcelona to a 4-1 victory over Villarreal at the Estadio de la Ceramica on Sunday.
Nigeria’s Samuel Chukwueze was handed his 33rd cap of the season, but he was at the receiving end of a thrashing as the Catalans ran riot.
A Pau Torres own goal gave Barca a third-minute lead, but Gerard Moreno equalized for the hosts ten minutes later after great work from Santi Cazorla.
However, two fantastic Messi assists allowed Suarez and Griezmann to restore and extend the visitor’s lead before youngster Fati sealed the win late on.
With the win, Barcelona remain four points behind leaders Real Madrid with four La Liga games left this campaign.
Villarreal, however, lost the chance to close the gap on fourth-placed Sevilla with their Champions League hopes slipping away from them.
In the Serie A, Super Eagles defender William Troost-Ekong and his Udinese teammates three away a two-goal lead to draw 2-2 at home to Genoa.